DESIGNER MONDO GUERRA DEBUTS FASHION COLLECTION INSPIRED BY THE EMOTIONAL REALITIES OF PEOPLE LIVING WITH PBC

Fashion takes on new meaning as acclaimed designer and Project Runway star Mondo Guerra unveil “All the Feelings with PBC,” a bold, multimedia experience that turns the invisible emotional journey of living with primary biliary cholangitis (PBC), into visible, wearable art. The event and program are supported by Gilead Sciences. PBC is a chronic autoimmune disease that progressively impacts the liver often causing symptoms including fatigue, itching, and abdominal discomfort.¹ In addition to physical symptoms, many individuals living with PBC experience emotional and psychosocial burdens, including anxiety, depression, and social isolation.²

Taking place at The Glasshouse at Bryant Park on September 10, 2025, just ahead of New York Fashion Week, the event will feature a fashion show spotlighting custom looks created by Guerra, inspired by in-depth interviews with people across the U.S. living with this autoimmune liver disease. Each garment brings to life the complex emotional, physical, and social dimensions of living with PBC.

“As someone who’s used fashion to tell my own health story, I know the power that creative expression holds in making invisible experiences visible,” said Mondo Guerra. “When I spoke with people living with PBC, I was struck by the strength it takes to carry both the physical symptoms and the emotional weight of the disease, often in silence. This collection is my way of honoring their voices and helping the world see what they go through every day.”

Following the fashion show, the event will host a live panel discussion featuring:

• Mondo Guerra, fashion designer and an HIV patient advocate
• People living with PBC, who inspired the collection
• Dr. Ilan S. Weisberg, MD, Chief, Division of Gastroenterology and Hepatology, NYP Brooklyn Methodist Hospital, offering clinical perspective on PBC and its impact

“Primary biliary cholangitis is more than an autoimmune disease. It’s a condition that impacts every facet of a person’s life, from their physical health to their emotional well-being,” said Dr. Weisberg. “Bringing those experiences into the public eye through fashion and storytelling helps challenge stigma, build empathy, and broaden awareness of what it truly means to live with PBC.”

Together, the panel will explore the intersection of chronic illness, identity, creative expression and what it means to make the invisible visible.

“All the Feelings with PBC” is part of a broader initiative by Gilead Sciences to amplify voices within the PBC community, build awareness of the disease’s emotional toll, and foster compassion and understanding through storytelling and art.

The event is by invitation only to select media and advocacy stakeholders. RSVP is required.

About PBC
PBC is a chronic, autoimmune disease of the bile ducts that affects approximately 130,000 Americans. PBC is more common in women and causes liver damage that can progress to liver failure and result in the need for liver transplant, if left untreated. The most common symptoms of PBC are pruritus (chronic itch) and fatigue, which up to 80% of people with PBC can experience and can profoundly compromise quality of life. Symptoms of PBC are often invisible to others and the journey to a PBC diagnosis can be long and challenging. There is currently no cure for PBC, and treatment goals include slowing disease progression and reducing the symptoms related to cholestasis (impaired bile flow), such as cholestatic itch. The effect is primarily measured by an improvement in liver biochemical tests, including the normalization of alkaline phosphatase (ALP) levels, an important marker of disease progression in PBC.

About Gilead Sciences in Liver Disease
For decades, Gilead has pioneered the way forward to improve the lives of people living with liver disease around the world. The company has helped to transform hepatitis C from a chronic condition into one that can be cured for millions of people. For individuals living with hepatitis B or D, Gilead's focus on advancing medicines drives hope that today’s research will turn into tomorrow’s cures. Beyond viral hepatitis, Gilead is working to deliver advanced treatments for people living with PBC. The commitment of Gilead doesn’t stop there. Through ground-breaking science and collaborative partnerships, the company strives to create healthier futures for everyone living with liver disease. Gilead remains devoted to a future without liver disease.

About Gilead Sciences
Gilead Sciences, Inc. is a biopharmaceutical company that has pursued and achieved breakthroughs in medicine for more than three decades, with the goal of creating a healthier world for all people. The company is committed to advancing innovative medicines to prevent and treat life-threatening diseases, including HIV, viral hepatitis, COVID-19, cancer and inflammation. Gilead operates in more than 35 countries worldwide, with headquarters in Foster City, California.

For more information about Gilead, please visit the company’s website at www.gilead.com, follow Gilead on X/Twitter (@Gilead Sciences) and LinkedIn (@Gilead-Sciences).

CONTACTS:
Blair Baumwell, Media
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Jacquie Ross, Investors
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